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E N Q U I R E R   L O C A L   N E W S   C O V E R A G E
Monday, February 22, 1999

Transplanting a baby liver




        When Sydni Quinlan became the fourth smallest infant ever to get a liver transplant at Children's Hospital, the operation cured her rare genetic condition. Making it happen, however, required overcoming several challenges:

        FINDING A DONOR: Babies need baby-sized livers, which requires surgeons to set weight limits for potential donors. Even though Sydni's new liver came from a child, it was still too big to use whole. Doctors transplanted the left lobe of the organ. Sydni was lucky. A matching liver, from a 22-pound child who died in Galveston, Texas, was found within four days of placing Sydni on a national waiting list.

        TRICKY SURGERY: Transplanting a liver takes about six-and-a half hours. It requires connecting several major blood vessels that are about 10 times smaller than those found in adults. In addition, the blood vessels from the baby and from the donor organ are different sizes. Connecting them requires complex suturing.

        FOLLOW-UP CARE: Discharged Feb. 8, Sydni will require daily blood tests at home plus frequent return hospital visits, starting at three times a week then tapering off over the next few months. She will take eight different medications — about 30 pills a day — on a strictly timed schedule; some for the rest of her life.

        OUTLOOK: Although she faces risks of infections and complication from her anti-rejection drugs, Sydni has a good chance of growing into adulthood. More than 55 percent of infants who get liver transplants live at least five years. Beyond that, experts are still tracking the long-term survivors. The longest running survivor so far, is a 31-year-old patient who got a liver transplant in Denver in 1970 at age three.

        Sources: United Network of Organ Sharing and Children's Hospital Medical Center

       



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