Sunday, May 30, 1999
Drugs for psychosis have big impact
BY ANNE MICHAUD
The Cincinnati Enquirer
Some of the most significant treatment breakthroughs in the last decade are for schizophrenia, a disorder that affects 2 million to 3 million Americans and 5,000 people in Hamilton County.
The market for anti-psychotic drugs is $2 billion and is projected to reach up to $6 billion in the next five years.
Some facts about the new drugs:
Clozaril: Approved in 1990, it was the first qualitative advance in drugs to treat schizophrenia since the 1950s. Made by Novartis AG, it reduced hallucinations while increasing social functioning. It eliminated a dreaded side-effect of older medications, which over time affected facial muscles, making a person's tongue stick out periodically or mouth chew constantly.
Risperdal: Introduced in 1993 by Johnson & Johnson, it improved on Clozaril by eliminating a potentially deadly side-effect. People taking Clozaril must have weekly blood tests to make sure their white blood-cell count has not dropped.
Zyprexa: Made by Eli Lilly and Co., it began selling in 1996 when the market for anti-psychotics was $1.5 billion. By 1998, sales of Zyprexa alone had reached $1.4 billion.
Sources: Bloomberg News, Eli Lilly
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