Friday, December 10, 1999
Local patients involved in research studies
BY TIM BONFIELD
The Cincinnati Enquirer
The findings in the Cleveland Clinic study published in The Lancet will come as no surprise to many Tristate patients who have been recently treated for blocked coronary arteries.
Doctors with the Ohio Heart Health Center and the Lindner Clinical Trials Center have been busy with stent research in recent years. In fact, some of the data in the Lancet study was based on patients treated in Cincinnati at Christ and University hospitals.
Especially at Christ Hospital, patients with single-vessel coronary artery blockages routinely get stents with the blood thinning drug ReoPro, instead of balloon angioplasty alone or traditional bypass surgery. Of about 1,600 such cases this year at Christ Hospital, about 90 percent of patients got stents and 80 percent of those also got ReoPro, said Dr. Dean Kereiakes, medical director of the Lindner Clinical Trials Center, and a member of the Ohio Heart group.
“We've already taken this into practice,” Dr. Kereiakes said. “Those who receive stents and ReoPro have a clear survival advantage.”
Elsewhere in the Tristate, many coronary disease patients do get stents instead of balloon angioplasty alone. But the use of ReoPro varies, Dr. Kereiakes said.
Lately, the Lindner Center has have been studying a variety of stent designs and whether other blood-thinning drugs work as well as ReoPro. It also has been testing various types of radiation treatments to prevent stents from reclogging.
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